Pigmented progressive purpuric dermatosis - 色素进行性紫癜性皮肤病
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ReferencesPigmented purpuric dermatoses (PPD) 是一组皮肤疾病，特征是毛细血管炎症引起皮下小面积出血。PPD 通常表现为红色至紫色斑点，随后随着含铁血黄素的再吸收，颜色转为金棕色。
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg disease 是最常见的 pigmented purpuric dermatoses (PPDs) 类型，这是一种慢性皮肤病，特征为红色或紫色小斑点，以及皮肤颜色增深（呈棕色、红色或黄色斑块）。PPD 可分为五种类型：Schamberg's purpura、Majocchi purpura、lichen aureus、Gougerot‑Blum purpura 和 eczematoid‑like purpura of Doucas and Kapetanakis。Schamberg disease (SD) 亦称为 progressive pigmentary dermatosis of Schamberg、purpura pigmentosa progressiva 和 Schamberg's purpura。该病主要影响男性，常见于小腿，也可累及大腿、臀部、躯干或手臂。
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
分析了113名PPD患者的信息，其中38名患者在本研究中接受了皮肤活检。最常见的临床类型是Schamberg 病 (60.5%)。除产后抑郁症外，其他伴随疾病还包括高血压（15.8%）、糖尿病（10.5%）等。用药史显示使用他汀类药物（13.2%）、β受体阻滞剂（10.5%）等。与产后抑郁症相关的可能因素包括近期上呼吸道感染（5.3%）、长时间站立导致立位压高（2.6%）和剧烈运动（2.6%）。36名患者（94.7%）接受了治疗——口服抗组胺药 (oral antihistamines)、pentoxifylline、外用类固醇 (topical steroids) 和/或光疗 (phototherapy)。
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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